Edit

Tag:

enzyme

Showing results out of

Year

27 November 2024 Photo of Sofia who is stretching her hands towards an illustrated elephant, which is offering her sweets. On the head of the elephant, is overlaid with a molecular model of the protein OGT, which has a similar shape.

Photo of Sofia who is stretching her hands towards an illustrated elephant, which is offering her sweets. On the head of the elephant, is overlaid with a molecular model of the protein OGT, which has a similar shape.

Cute molecules and the scientists who adore them: Sofia Rucli

Sofia Rucli, postdoc at EMBL Rome, talks about her relationship with the protein OGT, a molecular ‘candy man’ of the cell.

PEOPLE & PERSPECTIVES

2024

people-perspectives

25 June 2024 In the front, a 3D model of three molecules bound together: METTL6 in (orange), serine tRNA synthetase in (shades of lilac) and serine tRNA (black). In the background an illustration of a construction site. Two trucks with ‘UGA’ and ‘AGA’ written on them are visible at the bottom.

In the front, a 3D model of three molecules bound together: METTL6 in (orange), serine tRNA synthetase in (shades of lilac) and serine tRNA (black). In the background an illustration of a construction site. Two trucks with ‘UGA’ and ‘AGA’ written on them are visible at the bottom.

An enzyme with a smart friend

EMBL Grenoble’s Kowalinski Group analysed the structure of an enzyme responsible for modifying tRNA molecules to fine-tune protein production. They discovered that to distinguish almost identical, yet different, tRNA molecules, the enzyme uses help from another enzyme – a type of cooperation…

SCIENCE & TECHNOLOGY

2024

science-technology

27 November 2023 Photo of two people brainstorming at the table covered with several papers and images related to the research project, such as the structure of the molecule, a map with the Solar Lake marked, photo of EMBL Hamburg, photo of Garo Antranikian looking into a microscope, pages of the manuscript, data graphs, and more.

Photo of two people brainstorming at the table covered with several papers and images related to the research project, such as the structure of the molecule, a map with the Solar Lake marked, photo of EMBL Hamburg, photo of Garo Antranikian looking into a microscope, pages of the manuscript, data graphs, and more.

Hamburg collaboration paves the way to cleaner technologies for industry

An interdisciplinary collaboration between Hamburg scientists has yielded new insights into the structure and function of a heat-resistant enzyme from an exotic microbe. In this interview, EMBL Hamburg’s Matthias Wilmanns and TUHH’s Garo Antranikian discuss how their collaboration developed and…

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

21 September 2023

Understanding the mechanisms of enzyme catalysis

Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…

SCIENCE & TECHNOLOGY

2023

science-technologytechnology-and-innovation

11 October 2022 Plastic bottles and an enzyme protein structure

Plastic bottles and an enzyme protein structure

Funding for researchers working on plastic recycling enzymes

EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.

2022

announcementsscience

26 October 2021 Photo of researcher using MGnify database

Photo of researcher using MGnify database

Novel enzymes for a Green Economy

Using metagenomic data to find novel enzymes for plastic degradation and beyond

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

2 March 2018 HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

Kendrew and Philipson Awards Winners 2018

EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson Awards

EMBL ANNOUNCEMENTS

2018

alumniembl-announcements

17 January 2018 With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

Pol III enzyme grips DNA and begins reading fast

EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

20 December 2017 In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

ERC grantee Stephen Cusack shares his vision for the next ten years

SCIENCE & TECHNOLOGY

2017

sciencescience-technology

7 December 2017 Superimposable structures of the active sites of human DNA polymerase and of a bacterial ribozyme

Superimposable structures of the active sites of human DNA polymerase and of a bacterial ribozyme

Enzymes’ superimposable structures revealed

EMBL scientists superimpose structures of two-metal-ion enzymes and reveal new potential drug targets

SCIENCE & TECHNOLOGY

2017

sciencescience-technology

3 May 2017

Futures: Phosphatases

ERC grantee Maja Köhn shares her vision for the next ten years

SCIENCE & TECHNOLOGY

2017

sciencescience-technology

29 October 2015 Enzyme Portal relaunched

Enzyme Portal relaunched

Enzyme research made easier

Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

14 February 2011 3D structure of Mycobacterium tuberculosis’ enzyme PriA

3D structure of Mycobacterium tuberculosis’ enzyme PriA

Two in one

In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The new findings…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

13 August 2009

Raising the alarm when DNA goes bad

Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular ‘alarm bell’ to alert the…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

28 May 2009

Sugarcoating fruit fly development

Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

4 February 2009 High resolution image of the key domain of the influenza virus polymerase. The active site responsible for RNA cleavage is shown in red. Its activity is crucial for the virus to multiply in human cells

High resolution image of the key domain of the influenza virus polymerase. The active site responsible for RNA cleavage is shown in red. Its activity is crucial for the virus to multiply in human cells

New findings reveal how influenza virus hijacks human cells

Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability to infect humans easily, new drugs and vaccines are desperately sought. Researchers at…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

30 May 2008

X chromosome exposed

Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

22 June 2007

New compound effectively treats fungal infections

A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory [EMBL] outstation in Grenoble, France. In the current issue of Science they describe…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

10 June 2007

Researchers shed light on shrinking of chromosomes

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two daughter cells at every division. Condensation, the shortening of chromosomes, allows the cell to handle such huge amounts of genetic material during cell…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

19 June 2005

A link between our body’s energy levels and a protein that wraps our DNA?

Living organisms need to sense the amount of energy that is available to them and regulate the activity of their genes accordingly. Scientists have made the unexpected finding that a histone protein, which wraps DNA into tight bundles and regulates gene activity, can bind a small molecule produced…

SCIENCE & TECHNOLOGY

2005

sciencescience-technology

No results found

Edit