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Employing a library of more than 1,000 chemicals, EMBL researchers and collaborators investigated how agrochemicals affect insect populations.
SCIENCE & TECHNOLOGY2024
science-technology
New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.
SCIENCE & TECHNOLOGY2024
sciencescience-technology
Simone Heber talks about studying RNA transport, organising the Bike Club at EMBL, and participating in the Ironman World Championship.
LAB MATTERSPEOPLE & PERSPECTIVES2024
lab-matterspeople-perspectives
EMBL researchers are stepping outside the lab and thinking outside the box to understand the basic principles that underlie the development and evolution of organismal characteristics.
2023
science
EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Like caterpillars turning into beautiful butterflies, fruit fly larvae have to go through metamorphosis to finish their development. However, despite the fruit fly Drosophila melanogaster being one of the best studied model organisms in biology, comparatively little attention has been given to this…
SCIENCE & TECHNOLOGY2021
picture-of-the-weekscience-technology
Researchers from EMBL Heidelberg have established an automated pipeline to create mutations in genomic enhancers, letting them watch evolution unfold before their eyes.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
We’ve all had wounds at certain times in our lives. But they heal due to the self-repairing mechanisms in the body.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
Not just another pretty fruit fly. This magenta and golden drosophila larva is lit up with a fluorescent molecule to help researchers study heart formation.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
While this may seem like a nebula made up of interstellar clouds of dust and ionised gases, this image isn’t of a galaxy beyond the Milky Way.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
Those heart-shaped cells aren't just for show. They help tell the story of two proteins working together
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
Beautiful flashes of blue colour help light the way for researchers to study cells in fruit fly larva that provide oxygen to tissues.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
The image shown here, taken by Daniel Rios-Barrera from the Leptin Group shows the cells of the early wing tissue of the fly during larval development.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
What may look like a branch of a tree with the first flower buds emerging after winter are, in fact, tracheal cells of a fruit fly larva and their nuclei.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
This technique provides a simple but effective way to study the functions of organs in living animals
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Fruit flies have something that we don’t have: they produce a protein called dumpy. This protein is the largest created by insects, and is comparable in size to the largest human protein – titin. While titin is vital for our muscle function, dumpy connects the soft cells of the insect’s…
SCIENCE & TECHNOLOGY2019
picture-of-the-weekscience-technology
Today’s picture of the week is not only a colourful one, it is also a snapshot of the vast number of shapes that the cells inside an animal body can adopt. How this variety comes about is investigated in the Leptin group at EMBL Heidelberg. To understand the shapes of the cells in fruit fly…
SCIENCE & TECHNOLOGY2019
picture-of-the-weekscience-technology
A conversation about art-science collaborations and the importance of drawing in biology.
PEOPLE & PERSPECTIVES2019
people-perspectivesscience
This image – resembling a network of rivers and canals – actually shows the tracheal tip cell of a fruit fly. Fruit flies are heavily used in research and they are a common model organism in developmental biology. Researchers at EMBL use the larvae of fruit flies to study tracheal cell…
SCIENCE & TECHNOLOGY2019
picture-of-the-weekscience-technology
The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study,…
SCIENCE & TECHNOLOGY2013
sciencescience-technology
This may look like yet another video of a dividing cell, but there’s a catch. You are looking at chromosomes (red) being pulled apart by the mitotic spindle (green), but it’s not a cell, because there’s no cell membrane. Like a child sucking an egg out of its shell, Ivo Telley from the…
SCIENCE & TECHNOLOGY2013
sciencescience-technology
What do you get when you dissect 10 000 fruit-fly larvae? A team of researchers led by the EMBL- European Bioinformatics Institute (EMBL-EBI) in the UK and the Max Planck Institute of Immunobiology and Epigenetics (MPI) in Germany has discovered a way in which cells can adjust the activity of many…
SCIENCE & TECHNOLOGY2012
sciencescience-technology
“This video shows a fruit fly embryo from when it was about two-and-a-half hours old until it walked away from the microscope as a larva, 20 hours later,” says Lars Hufnagel, from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. “It shows all the hallmarks of fruit fly…
SCIENCE & TECHNOLOGY2012
sciencescience-technology
Like any law-abiding train passenger, a molecule called oskar RNA carries a stamped ticket detailing its destination and form of transport, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. They show that for this molecule, moving in the…
SCIENCE & TECHNOLOGY2012
sciencescience-technology
If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…
SCIENCE & TECHNOLOGY2012
sciencescience-technology
The scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, who ‘fathered’ the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the…
SCIENCE & TECHNOLOGY2010
sciencescience-technology
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…
SCIENCE & TECHNOLOGY2010
sciencescience-technology
Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…
SCIENCE & TECHNOLOGY2009
sciencescience-technology
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that…
SCIENCE & TECHNOLOGY2008
sciencescience-technology
Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear. Now researchers from the European Molecular…
SCIENCE & TECHNOLOGY2007
sciencescience-technology
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