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fruit fly

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11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

sciencescience-technology

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

12 July 2021 Close-up illustration of the Kinesin-1 protein, intertwined with the aTm1 protein in a helix, next to loopy mRNA molecules.

A model of cooperation for transporting mRNA

Science & Technology EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.

2021

sciencescience-technology

2 March 2021

Sleeping beauty

Science & Technology Like caterpillars turning into beautiful butterflies, fruit fly larvae have to go through metamorphosis to finish their development. However, despite the fruit fly Drosophila melanogaster being one of the best studied model organisms in biology, comparatively little attention has been given to this…

2021

picture-of-the-weekscience-technology

14 October 2020

Seeing evolution happening before your eyes

Science & Technology Researchers from EMBL Heidelberg have established an automated pipeline to create mutations in genomic enhancers, letting them watch evolution unfold before their eyes.

2020

sciencescience-technology

6 October 2020 A filmstrip showing the healing process of a wound on cellular level.

Time heals all wounds

Science & Technology We’ve all had wounds at certain times in our lives. But they heal due to the self-repairing mechanisms in the body.

2020

picture-of-the-weekscience-technology

15 September 2020 Fluorescent microscopic image of fruit fly larva with tubular heart cells in gold and the remainder of image in magenta

Fruit fly with a heart of gold

Science & Technology Not just another pretty fruit fly. This magenta and golden drosophila larva is lit up with a fluorescent molecule to help researchers study heart formation.

2020

picture-of-the-weekscience-technology

8 September 2020 A network of tubes and cells in red and blue.

Not a galaxy far, far away

Science & Technology While this may seem like a nebula made up of interstellar clouds of dust and ionised gases, this image isn’t of a galaxy beyond the Milky Way.

2020

picture-of-the-weekscience-technology

1 September 2020 larval fruit fly cells

A luminous larval love light

Science & Technology Those heart-shaped cells aren't just for show. They help tell the story of two proteins working together

2020

picture-of-the-weekscience-technology

25 August 2020 Fruit fly larval cells looking like blue lightning

Breathing beneath the skin

Science & Technology Beautiful flashes of blue colour help light the way for researchers to study cells in fruit fly larva that provide oxygen to tissues.

2020

picture-of-the-weekscience-technology

19 August 2020 An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

Science & Technology Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.

2020

sciencescience-technology

6 May 2020

Wings without wings

Science & Technology The image shown here, taken by Daniel Rios-Barrera from the Leptin Group shows the cells of the early wing tissue of the fly during larval development.

2020

picture-of-the-weekscience-technology

14 April 2020

Gazing at healing wounds

Science & Technology What may look like a branch of a tree with the first flower buds emerging after winter are, in fact, tracheal cells of a fruit fly larva and their nuclei.

2020

picture-of-the-weekscience-technology

25 September 2019

A giant called dumpy

Science & Technology Fruit flies have something that we don’t have: they produce a protein called dumpy. This protein is the largest created by insects, and is comparable in size to the largest human protein – titin. While titin is vital for our muscle function, dumpy connects the soft cells of the insect’s…

2019

picture-of-the-weekscience-technology

20 August 2019

When life takes shape

Science & Technology Today’s picture of the week is not only a colourful one, it is also a snapshot of the vast number of shapes that the cells inside an animal body can adopt. How this variety comes about is investigated in the Leptin group at EMBL Heidelberg.  To understand the shapes of the cells in fruit fly…

2019

picture-of-the-weekscience-technology

1 July 2019 The dynamic process of cell division.

Drawing knowledge

People & Perspectives A conversation about art-science collaborations and the importance of drawing in biology.

2019

people-perspectivesscience

21 May 2019

From fruit flies to cancer treatment

Science & Technology This image – resembling a network of rivers and canals – actually shows the tracheal tip cell of a fruit fly. Fruit flies are heavily used in research and they are a common model organism in developmental biology. Researchers at EMBL use the larvae of fruit flies to study tracheal cell…

2019

picture-of-the-weekscience-technology

7 August 2013

Cells eat themselves into shape

Science & Technology The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study,…

2013

sciencescience-technology

17 January 2013

The cell that isn’t

Science & Technology This may look like yet another video of a dividing cell, but there’s a catch. You are looking at chromosomes (red) being pulled apart by the mitotic spindle (green), but it’s not a cell, because there’s no cell membrane. Like a child sucking an egg out of its shell, Ivo Telley from the…

2013

sciencescience-technology

19 July 2012 The female (left) fruit fly, Drosophila melanogaster, is larger than the male (right). Image credit: EMBL.

Of flies and men

Science & Technology What do you get when you dissect 10 000 fruit-fly larvae? A team of researchers led by the EMBL- European Bioinformatics Institute (EMBL-EBI) in the UK and the Max Planck Institute of Immunobiology and Epigenetics (MPI) in Germany has discovered a way in which cells can adjust the activity of many…

2012

sciencescience-technology

3 June 2012

Video Release: Filming life in the fast lane

Science & Technology “This video shows a fruit fly embryo from when it was about two-and-a-half hours old until it walked away from the microscope as a larva, 20 hours later,” says Lars Hufnagel, from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. “It shows all the hallmarks of fruit fly…

2012

sciencescience-technology

18 March 2012

Need for speed

Science & Technology Like any law-abiding train passenger, a molecule called oskar RNA carries a stamped ticket detailing its destination and form of transport, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. They show that for this molecule, moving in the…

2012

sciencescience-technology

2 February 2012 Fruit fly embryo showing the cells that will become the gut and heart

Collective action

Science & Technology If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…

2012

sciencescience-technology

4 July 2010 The Fly Digital Embryo at different developmental stages, with cell nuclei coloured according to how fast they were moving (from blue for the slowest to orange for the fastest). The fruit fly embryo is magnified around 250 times. IMAGE: Philipp Keller

Digital Embryo gains wings

Science & Technology The scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, who ‘fathered’ the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the…

2010

sciencescience-technology

24 June 2010 These microscopy images show that a protein from the NSL complex (green) and MOF (red) both bind to all chromosomes in male (right) and female (left) fruit flies - overlap is shown in purple. On the male X chromosome, MOF binds not only to promoter regions but also to the body of the genes, generating a brighter signal (pink). Image credits: Akhtar/EMBL.

A life-changing partnership

Science & Technology Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…

2010

sciencescience-technology

4 November 2009 fluorescence microscopy images of fruit fly embryos

Deciphering the regulatory code

Science & Technology Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…

2009

sciencescience-technology

30 May 2008

X chromosome exposed

Science & Technology Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that…

2008

sciencescience-technology

16 May 2007

Mechanism of microRNAs deciphered

Science & Technology Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear. Now researchers from the European Molecular…

2007

sciencescience-technology

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