Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…
2024
science-technology
Science & Technology A study from the Hackett group at EMBL Rome led to the development of an epigenetic editing system that allows to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation.
2024
science-technology
Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.
2024
sciencescience-technology
Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
2022
sciencescience-technology
Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
2022
sciencescience-technology
Lab MattersPeople & Perspectives Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.
2022
lab-matterspeople-perspectives
Science & Technology A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
sciencescience-technology
Science & Technology Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
2020
sciencescience-technology
Science & Technology EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
2020
sciencescience-technology
Science & Technology EMBL researchers investigate the role of a histone protein in regulating gene expression
2020
sciencescience-technology
People & Perspectives EMBL’s next Director General reflects on the questions that drive her research
2018
people-perspectivesscience
Science & Technology EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
sciencescience-technology
Science & Technology EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories
2018
sciencescience-technology
Science & Technology Network of genes linked to development of diabetes
2018
sciencescience-technology
Science & Technology EMBL scientists show that some promoters can act as enhancers and vice versa
2018
sciencescience-technology
Science & Technology EMBL scientists unveil how 3D chromatin structure affects RNA splicing
2017
sciencescience-technology
People & Perspectives New group leader based in Grenoble aims to unveil the mechanisms of RNA editing
2017
people-perspectivesscience
Connections James Sharpe, Head of EMBL Barcelona, co-chairs the morphogenetic engineering-themed conference
2017
connectionsevents
People & Perspectives Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
2017
people-perspectivesscience
Science & Technology Tim Richmond looks back on the work that revealed the high-resolution structure of the nucleosome
2017
eventsscience-technology
Science & Technology EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing
2017
sciencescience-technology
Science & Technology ERC grantee Eileen Furlong shares her vision for the next ten years
2017
sciencescience-technology
Science & Technology New mechanism revealed
2017
sciencescience-technology
Science & Technology From shared interests at a conference to a surprising discovery
2016
sciencescience-technology
Science & Technology How stem cells resist change
2016
sciencescience-technology
Science & Technology How T-cells are trained on what not to kill
2015
sciencescience-technology
Science & Technology European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
2015
sciencescience-technology
New Bar-ChIP method makes it easier to search for epigenetic marks in many samples at once
2015
science
First experimental proof that a key cellular machine forms by uniting pre-assembled modules.
2015
science
The important thing is forming good biological questions, says new group leader in Genome Biology.
2014
science
Experts from multiple fields come together to understand how the instructions in genes are read
2014
events
From vitamin C to safe matches, a sample of notable scientists from our newest prospect member state.
2014
science
Science & Technology Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
sciencescience-technology
Science & Technology Surprising finding: enhancers find their targets long before activation in Drosophila embryos
2014
sciencescience-technology
Science & Technology Scientists determine the structure of auxin response factors: daisy-chains that regulate gene expression
2014
sciencescience-technology
Science & Technology Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
sciencescience-technology
Science & Technology How a DNA stretch influences face formation and contributes to common congenital malformations
2014
sciencescience-technology
Science & Technology During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and…
2013
sciencescience-technology
Science & Technology As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…
2012
sciencescience-technology
Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to…
2011
sciencescience-technology
Science & Technology In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body’s stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit (MMPU), a collaboration between the European Molecular…
2011
sciencescience-technology
Science & Technology Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…
2010
sciencescience-technology
Science & Technology Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because…
2010
sciencescience-technology
Science & Technology Recent research at the European Molecular Biology Laboratory (EMBL) reveals new insights into how cells achieve equality between the sexes. A new link discovered between the membrane surrounding the nucleus and the male X-chromosome in fruit flies may play a crucial role in determining how active…
2006
sciencescience-technology
Science & Technology Living organisms need to sense the amount of energy that is available to them and regulate the activity of their genes accordingly. Scientists have made the unexpected finding that a histone protein, which wraps DNA into tight bundles and regulates gene activity, can bind a small molecule produced…
2005
sciencescience-technology
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