Human immune system is ‘ready to go’ long before birth
The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained during early life
2024
announcements
Read the latest Issue
Cancer drug resistance causes and categories identified
Researchers uncover that DNA changes that cause cancer drug resistance can be grouped into four categories, and identify possible new therapeutic targets.
2024
announcements
Funding awarded to develop a global Pathogen Data Network
EMBL-EBI and colleagues from other 11 institutes commit to pathogen data sharing project.
2024
announcements
Polygenic Score (PGS) Catalog increases diversity and usability of genetic data
Science & Technology Addition of data from more diverse populations to the Polygenic Score (PGS) Catalog and a new software tool for PGS calculation could help produce more equitable disease risk predictions.
2024
science-technologytechnology-and-innovation
EMBL-EBI’s open data resources for biodiversity and climate research
Science & Technology EMBL-EBI data resources help advance biodiversity and climate change research by enabling scientists to study species interactions, evolutionary processes, ecosystem health, and more.
2024
science-technologytechnology-and-innovation
Why clinical trials stop: the role of genetics
Science & Technology Using machine learning to analyse the genetic factors behind early clinical trial termination, researchers find a link between genetic evidence and trial outcome.
2024
research-highlightsscience-technology
DECIPHER v11.27 release
The v11.27 DECIPHER release is out now. Find out about the new features and improvements.
2024
updates-from-data-resources
The EMBL evolution: Ewan Birney on open data and the ethos of excellence
People & Perspectives Ewan Birney reflects on his time at EMBL and the development of the organisation through a commitment to open data and nurturing scientific talent.
2024
people-perspectivesperspectives
Welcome: Mallory Freeberg
People & Perspectives The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.
2024
people-perspectivesperspectives
Ancient environmental DNA provides solutions for global food security challenges
EMBL Announcements Researchers explore genetic diversity found in ancient environmental DNA to help modern agricultural practices.
2024
announcementsembl-announcements
Genetic mosaicism more common than thought
Science & Technology Blood stem cells from healthy people carry major chromosomal alterations, a study in Nature Genetics by researchers at the Max Delbrück Center and the European Molecular Biology Laboratory (EMBL) finds. The discovery suggests that we are all genetic mosaics, which may contribute to ageing-related…
2024
science-technology
DECIPHER v11.26 release
The latest DECIPHER release includes AlphaMissense scores, links to the Open Targets Platform and more.
2024
updates-from-data-resources
Predicting cancer risk on the basis of national health data
Science & Technology Large-scale study uses data from Danish health registries to predict individual risks of developing cancer
2024
research-highlightsscience-technology
AlphaMissense data integrated into Ensembl, UniProt, DECIPHER and AlphaFold DB
The integration enables researchers to easily access AI-generated scores estimating how likely genetic variants are to be pathogenic
2024
technology-and-innovation
Ensembl 112 has been released
Ensembl 112 and the corresponding release of Ensembl Genomes 59 has released. This includes exciting new fish species, many more drosophila species and new VEP updates.
2024
updates-from-data-resources
MSD joins the Open Targets consortium
EMBL Announcements MSD joins as the latest partner in the Open Targets consortium, enhancing the initiative’s collaborative efforts in drug discovery.
2024
announcementsembl-announcements
Researchers aim to use quantum computing to assemble and analyse pangenomes
Science & Technology Experts in quantum computing and genomics to develop new methods and algorithms to process biological data.
2024
announcementsscience-technology
‘Exhausted’ immune cells in healthy women could be target for breast cancer prevention
Science & Technology New study uncovers the potential of immunotherapy in preventing breast cancer and creates the openly available Human Breast Cell Atlas.
2024
research-highlightssciencescience-technology
Using Data Hubs to analyse SARS-CoV-2 and other pathogen sequences
The SARS-CoV-2 Data Hubs are a set of tools coupled with infrastructure that support four components: the submission, analysis, presentation and visualisation of SARS-CoV-2 raw read data, and its resulting analyses. What makes Data Hubs attractive is a unique set of features: A new publication in…
2024
updates-from-data-resources
The malaria parasite generates genetic diversity using an evolutionary ‘copy-paste’ tactic
Science & Technology Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.
2024
announcementssciencescience-technology
Team SAMBAI: addressing cancer disparities in recent African heritage populations
Science & Technology An international team of researchers aim to combine social determinants of health with genomics, immune profiling, and exposomics data to tackle cancer inequities at an unprecedented scale.
2024
announcementssciencescience-technology
First datasets available in the Federated EGA Network
The Federated European Genome-phenome Archive (FEGA) marks a significant milestone with the release of its first datasets.
2024
announcements
DECIPHER v11.24 Released
Version 11.24 of DECIPHER introduces a new ACMG/AMP pathogenicity interface for sequence variant predictions, displays ClinGen Variant Curation Expert Panel recommendations on gene pages, and updates ACMG secondary finding information to v3.2.
2024
updates-from-data-resources
We are EMBL: Jacqueline Toussaint on strange bacteria and bioinformatics
Lab MattersPeople & Perspectives Jacqueline shares her experience of EMBL's international PhD programme.
2024
lab-matterspeople-perspectives
Ensembl 111 has been released
The Ensembl 111 features a range of new Ensembl VEP plugins and updated agricultural, fish, plant and metazoa species.
2024
updates-from-data-resources
The Biodiversity Cell Atlas: charting cellular diversity on Earth
A $3.8 million grant from the Gordon and Betty Moore Foundation will help researchers lay groundwork for the Biodiversity Cell Atlas.
2024
announcements
Six takeaways from the EMBL conference Cancer Genomics 2023
Science & Technology Approximately 300 scientists met up at EMBL Heidelberg to unravel the centuries-old puzzle of cancer through the modern lens of genomics.
2024
eventsscience-technology
Unravelling the role of immune cells in early lung development
Science & Technology Researchers reveal that healthy lung development hinges on immune-epithelial crosstalk, with implications for respiratory diseases.
2023
research-highlightsscience-technology
The Global Biodiversity Portal: enabling biodiversity research worldwide
Science & Technology The new initiative brings together genomic data from various biodiversity projects to aid conservation and biodiversity efforts.
2023
announcementssciencescience-technology
Extending the network of infectious disease data portals: developments in Sweden and The Netherlands
Two new data portals are set to support infectious disease monitoring and research across Europe; the Swedish Pathogens Data Portal and the Netherlands COVID-19 Data Portal.
2023
updates-from-data-resources
EMBL-EBI co-leads on research programme to help treat relapsed childhood cancers
Leading charities Children with Cancer UK and Cancer Research UK will co-fund a major £5.5 million research programme to advance precision medicine for relapsed childhood cancers.
2023
announcements
Starting is easy, sustaining is hard
Where to start when thinking about the sustainability of informatics projects
2023
perspectives
Deciphering the data deluge: how large language models are transforming scientific data curation
EMBLetc Large language models are changing the way we carry out scientific data curation, annotation, and research, setting the stage for a more efficient understanding of scientific literature
2023
Embracing the genome sequencing revolution
EMBLetc EMBL’s Genomics Core Facility provides end-to-end support to researchers across Europe and beyond and stands at the forefront of scientific breakthroughs.
2023
Genes, cells, and embryos in development and evolution: Pere Alberch, 25 years on
Connections Scientists from the MELIS department at UPF and EMBL Barcelona have organised a symposium to discuss the work of the visionary Catalan scientist Pere Alberch, who passed away 25 years ago.
2023
connectionsevents
ggCaller: The next step in scaling up bacterial genome annotation
The Lees group develops a tool that can scale up bacterial genome annotation.
2023
research-highlights
We are EMBL: Valentina Lorenzi on human reproductive development
Lab MattersPeople & Perspectives PhD student Valentina Lorenzi is using single-cell sequencing data to create a map of the developing human reproductive system.
2023
lab-matterspeople-perspectivesperspectives
Understanding the mechanisms of enzyme catalysis
Science & Technology Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…
2023
science-technologytechnology-and-innovation
Welcome: David Hulcoop
Lab MattersPeople & Perspectives David Hulcoop discusses how his experience bridging organisational cultures will help address critical challenges in drug discovery and target selection at Open Targets.
2023
announcementslab-matterspeople-perspectives
Uncovering the mechanisms underlying lack of response to immunotherapy
Science & Technology New research improves understanding of the molecular mechanisms behind why some cancers respond to immunotherapy and others don't.
2023
research-highlightssciencescience-technology
Novel algorithm able to detect mutations in single-cell sequencing data sets
Science & Technology SComatic enables researchers to link genotype to phenotype using only single-cell profiling data
2023
research-highlightssciencescience-technology
Filling the skills gap to advance genomic medicine: an interview with Emily Perry
Lab MattersPeople & Perspectives By upskilling researchers on bioinformatics skills and tools, EMBL alumna Emily Perry is helping to make genomic medicine more accessible.
2023
lab-matterspeople-perspectivesperspectives
refget v2.0 links the hidden dictionaries of DNA
The GA4GH standard refget quietly helps decipher millions of genomes sequenced worldwide, and it just got better.
2023
technology-and-innovation
Ensembl 110 has been released
Ensembl 100 release brings exciting updates, such as the addition of regulation data to 5 animal genomes studied extensively in agriculture.
2023
updates-from-data-resources
EMBL-EBI’s new building set to support data growth and innovative partnerships
EMBL AnnouncementsLab Matters Construction begins on EMBL-EBI's new building named after Janet Thornton.
2023
announcementsembl-announcementslab-matters
DECIPHER database for rare diseases joins EMBL-EBI
EMBL Announcements Closer collaborations with EMBL-EBI data resources set to further develop and grow this unique rare disease platform.
2023
announcementsembl-announcementsscience
Pathogens Portal: The new gateway to public pathogen data
Science & Technology Enabling researchers worldwide to share and analyse pathogen data generated across the world
2023
sciencescience-technologytechnology-and-innovation
Supporting the development of hologenomic approaches for more sustainable animal feeds
Science & Technology HoloFood, the first consistent collection of multiomic data about chicken and salmon gut microbiomes, set to enable the development of better animal feeds.
2023
sciencescience-technologytechnology-and-innovation
Genomic medicine: ushering in a new era in healthcare
Science & Technology EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivessciencescience-technology
ProtVar: understanding missense variation in humans
Science & Technology A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencescience-technologytechnology-and-innovation
We are EMBL: Carolin Sauer on supporting cancer research
Lab MattersPeople & Perspectives Postdoctoral researcher Carolin Sauer is leveraging long-read sequencing to develop new detection methods for various cancers.
2023
lab-matterspeople-perspectivesresearch-highlights
Managing a bioinformatics core facility
BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.
2023
technology-and-innovation
The story of Clustal: democratising sequence alignments
EMBLetc Desmond Higgins, 2023 Lennart Philipson Award winner, discusses his time at EMBL and his research developing sequence alignment tools.
2023
What happens when chromosomes shatter
Science & Technology Understanding chromothripsis offers insights into how cancer develops.
2023
research-highlightsscience-technology
A more diverse human reference genome
Science & Technology The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.
2023
announcementssciencescience-technology
Bioinformatics powers international effort to map gene function
Lab MattersScience & Technology EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-mattersscience-technology
The Human Genome Project at 20: interview with Ewan Birney
Lab MattersPeople & Perspectives On the 20th anniversary of the Human Genome Project, we look back at its history, wonder and potential.
2023
lab-matterspeople-perspectivesperspectives
WormBase ParaSite 18 released
Science & Technology WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.
2023
science-technologyupdates-from-data-resources
Human genome editing: regulations, risks, and ethical considerations
Lab MattersPeople & Perspectives Scientists have the technology to edit the human genome. But when should they, and who contributes to these decisions?
2023
lab-matterspeople-perspectivesperspectives
MAPLE: a phylogenetic tool for pandemic-scale genome data
Science & Technology EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.
2023
research-highlightssciencescience-technology
Building a bioinformatics community at the nf-core hackathon
Connections Darwin Tree of Life project improves bioinformatics tools for biodiversity data analysis
2023
connectionstechnology-and-innovation
The ‘long read’ for cancer
Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.
2023
science
Genomic science to support conservation efforts: an interview with Lara Urban
Using long-read sequencing and machine learning approaches, EMBL alumna Lara Urban is making a difference in the field of One Health.
2023
perspectives
Large-scale study enables new insights into rare eye disorders
EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
Open data for biodiversity: an EMBL-EBI 2022 round-up
As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
New Job Dispatcher website launched
EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development. The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…
2023
updates-from-data-resources
Molecules to Ecosystems: Jo McEntyre on data services
Lab MattersPeople & Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-matterspeople-perspectivesperspectives
Welcome: Hanh Vu
Lab MattersPeople & Perspectives Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.
2023
lab-matterspeople-perspectives
Ensembl 109 has been released
Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.
2023
updates-from-data-resources
Leveraging long-read sequencing for cancer genomics
Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
Machine learning to identify and prioritise drug targets
Science & Technology Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencescience-technologytechnology-and-innovation
Darwin Tree of Life: first 500 genome assemblies released as project creates a buzz
Science & Technology We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivessciencescience-technology
Molecules to Ecosystems: Rob Finn on the Microbial Ecosystems transversal theme
Lab MattersPeople & Perspectives Rob Finn, one of the co-chairs of the Microbial Ecosystems theme, discusses his work, the challenges of multidisciplinary research, and how the theme is already helping to promote the exchange of scientific ideas.
2023
lab-matterspeople-perspectives
BOSS-RUNS: streamlining dynamic nanopore sequencing
Science & Technology A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightssciencescience-technology
Genomic Data Infrastructure – integrating genomics into healthcare
EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Unleashing the biotechnology potential of euglenoids
An ambitious project to sequence the genomes of all known species of euglenoids will drive research on biofuels and sustainable foods.
2022
announcements
Open Targets consortium welcomes Genentech as newest member
Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Open science for climate justice
Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
New molecular microscopy uncovers how breast cancer spreads
Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
Ensembl 108 has been released
We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…
2022
updates-from-data-resources
ArrayExpress interface now retired
Data continues to be available in BioStudies.
2022
updates-from-data-resources
Biodiversity Genomics Europe: addressing biodiversity loss through genomics
European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
European institutes commit to data access across borders
Connections The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsconnectionsscience
Life Science Alliance starts new chapter
ConnectionsLab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.
2022
connectionslab-matters
CNest: a new method for copy number variation analysis
Science & Technology A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightssciencescience-technology
New antibiotic resistance genes identified in tuberculosis
Science & Technology International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightssciencescience-technology
Uncharted territories in the human genome
Science & Technology Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightssciencescience-technology
Ensembl 107 has been released
The Ensembl 107 release contains updates to regulatory annotations and updated vertebrate and metazoan species.
2022
updates-from-data-resources
Interactive data visualisation for Single Cell Expression Atlas
Using powerful data visualisation and interactive search results across datasets allows users to explore hypotheses across a range of metadata, and discover new insights backed by expertly curated, consistently reanalysed single cell sequencing data. Searching for metadata, allows a powerful…
2022
updates-from-data-resources
Darwin Tree of Life at the Royal Society Summer Science Exhibition
A closer look at how genome sequencing is helping us protect biodiversity and our latest public engagement activities
2022
announcements
Supporting the African BioGenome Project to build bioinformatics capacity
ConnectionsLab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementsconnectionslab-matters
Impact of DNA mutations on blood cell production uncovered
Science & Technology Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightssciencescience-technology
A machine learning approach for allocating gene function
Science & Technology Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencescience-technologytechnology-and-innovation
Fergal Martin – Eukaryotic Annotation Team Leader
Lab MattersPeople & Perspectives Fergal Martin discusses the importance of open access data and his work in different biodiversity initiatives
2022
lab-matterspeople-perspectives
Organisations should embrace open science faster – interview with Prof. Dame Janet Thornton
Lab MattersPeople & Perspectives Janet Thornton, the inaugural winner of the FEBS Journal Open Science Award, explains the importance and impact of open science.
2022
lab-matterspeople-perspectivesperspectives
Peter Harrison – Genome Analysis Team Leader
Lab MattersPeople & Perspectives Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.
2022
lab-matterspeople-perspectives
Greater than the sum of our genes: DNA does not define us
Lab Matters Ewan Birney discusses the input of both genetics and our environment in making us who we are
2022
lab-mattersperspectives
The MANE collaboration: working together to support genome science
Science & Technology Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightssciencescience-technology
Welcome: John Lees
Lab MattersPeople & Perspectives John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.
2022
lab-matterspeople-perspectives
Pathogen data sharing – key to pandemic preparedness
Science & Technology Researchers lay out a set of principles for open genomic data sharing or pathogens
2022
perspectivesscience-technology
Genomic sequencing aids the global Tuberculosis fight
Science & Technology Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivessciencescience-technology
New genetic data policy must promote biodiversity conservation
Science & Technology Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementssciencescience-technology
Pfizer joins the Open Targets consortium
Connections Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsconnectionsscience
Genomic data for biodiversity – a global challenge
Science & Technology An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivessciencescience-technology
Can data help feed a hungry world?
Science & Technology How genomics, open data, and multidisciplinary science can improve food security.
2021
sciencescience-technology
Genomic sequencing to strengthen biodiversity
Science & Technology The Darwin Tree of Life project is an unprecedented initiative sequencing 70,000 species
2021
sciencescience-technology
Genomic tracking of the COVID-19 pandemic in England
Science & Technology Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
sciencescience-technology
Charting a multi-omic universe
Science & Technology A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.
2021
sciencescience-technology
Common medications accumulate in gut bacteria
Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
sciencescience-technology
Welcome: Sarah Dyer
Lab MattersPeople & Perspectives EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
2021
lab-matterspeople-perspectives
Joining forces to solve global challenges
ConnectionsLab Matters EMBL and the Swedish Science for Life Laboratory sign agreement to advance science together.
2021
connectionslab-matters
Genomic surveillance of SARS-CoV-2 in England
Science & Technology The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.
2021
sciencescience-technology
Piecing together the best reference genome
Science & Technology Researchers reveal the best technology for assembling reference genomes.
2021
sciencescience-technology
Genome sequencing accelerates cancer detection
Science & Technology The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
sciencescience-technology
New clues to a 500-year old mystery about the human heart
Science & Technology An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
sciencescience-technology
The curious genome of the tuatara, an ancient reptile in peril
Science & Technology A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
sciencescience-technology
Unparalleled inventory of the human gut ecosystem
Science & Technology An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
sciencescience-technology
Two EMBL scientists become EMBO Members
EMBL AnnouncementsLab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.
2020
embl-announcementslab-matters
Welcome: Ellie McDonagh
Lab MattersPeople & Perspectives Open Targets welcomes new Informatics Science Director
2020
lab-matterspeople-perspectives
Five things you probably didn’t know about the Human Genome Project
Science & Technology Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
sciencescience-technology
Unpicking the complexity of DNA mutations
Science & Technology DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
sciencescience-technology
Distinguishing coronavirus genome mutations from inadvertent errors
Science & Technology EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
sciencescience-technology
Understanding the role of our genes in SARS-CoV-2 infections
Science & Technology EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…
2020
sciencescience-technology
DNA damage and faulty repair jointly cause mutations
Science & Technology DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
sciencescience-technology
Welcome: Isidro Cortés-Ciriano
People & Perspectives Exploring the cancer genomics labyrinth
2019
people-perspectivesscience
Understanding molecular mechanisms of ageing
Science & Technology Understanding how ageing works at a molecular level
2019
sciencescience-technology
How coding opens up scientific data
Science & Technology The increasing importance of code in the biological sciences
2019
sciencescience-technology
Life with the endangered kākāpō
Science & Technology Using genomics to help endangered species
2019
sciencescience-technology
Welcome: Jessica Vamathevan
Lab Matters Building bonds between academia and industry
2019
lab-matters
Funding for bioinformatics technical infrastructure
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Facilitating transcontinental human data exchange
Science & Technology Federated data sharing will now be possible on an unprecedented scale
2019
sciencescience-technology
An in silico hope for biology: machine learning
Lab MattersScience & Technology How EMBL scientists are using machine learning to advance biology
2018
lab-mattersscience-technology
Sanofi joins Open Targets
ConnectionsLab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
connectionslab-matters
Deleting genes to study how germ cells are born
Science & Technology How embryonic stem cells develop into the germ line
2018
sciencescience-technology
Looking for life using geobiology
Science & Technology Meet the organisers of EMBO’s first course on molecular geobiology
2018
eventsscience-technology
Leukaemia roots detectable years before diagnosis
Science & Technology Acute myloid leukaemia risk could be detected years before diagnosis
2018
sciencescience-technology
New insights into the origins of cancer
Science & Technology What worms can tell us about cancer
2018
sciencescience-technology
The genetic risk factors for depression
Science & Technology Is depression in your genes?
2018
sciencescience-technology
Loops in DNA affect which proteins are coded
Science & Technology EMBL scientists unveil how 3D chromatin structure affects RNA splicing
2017
sciencescience-technology
Research highlights
Science & Technology A summary of recent research highlights from EMBL
2017
sciencescience-technology
UK pupils and scientists explore parasite problem
Lab Matters EMBL-EBI and collaborators engage schools in a large-scale genome decoding project
2017
eventslab-matters
UK Biobank partners with the EGA
Connections Genetic data from a major cohort now distributed via EMBL-EBI
2017
connectionsscience
Futures: Genome regulation
Science & Technology ERC grantee Eileen Furlong shares her vision for the next ten years
2017
sciencescience-technology
Building bioinformatics capacity in Africa
People & Perspectives EMBL alumna Nicola Mulder reflects on her pan-African bioinformatics project and its impact
2017
alumnipeople-perspectives
Genetic switches can change shape
Science & Technology EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
sciencescience-technology
Buffering mechanism protects embryonic development
Science & Technology New mechanism revealed
2017
sciencescience-technology
Collaboration is beautiful
Science & Technology Where design meets bioinformatics, new scientific perspectives abound.
2016
sciencescience-technology
Mapping early development
Science & Technology “Like getting hold of a microscope for the first time”
2016
sciencescience-technology
Scientific twins
Science & Technology Collaborations shorten distance between EMBL Heidelberg, Germany, and CEITEC in Brno, Czech Republic
2016
sciencescience-technology
Microbiomes: Our humble overlords
Science & Technology What's a microbiome? How on Earth do they work?
2016
sciencescience-technology
Unexpected link in protein production
Science & Technology From shared interests at a conference to a surprising discovery
2016
sciencescience-technology
Towards personalised breast cancer treatment
Science & Technology Largest-ever study of breast cancer genomes reveals new genes and mutations
2016
sciencescience-technology
Foetus, or placenta?
Science & Technology Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
sciencescience-technology
![A new tool for single-cell genomics helps us better understand differences between T cell populations. [Illustration: Spencer Phillips, EMBL-EBI]](https://www.embl.org/news/wp-content/uploads/2016/03/TCell_news_EMBL-e1457443531496-300x205.jpg)
Immunology meets single-cell sequencing
Science & Technology TraCeR: new method for studying T cells opens up opportunities to explore immune responses
2016
sciencescience-technology
Mapping malaria
Science & Technology First detailed atlas of start points for genes expression in malaria-causing parasite
2016
sciencescience-technology
Drugging bacteria
Science & Technology Commonly used diabetes drug metformin impacts gut bacteria more than disease itself
2015
sciencescience-technology
BioBeat15: Translating genomics into biobusiness
Connections Connecting entrepreneurs and world leaders in genomics to address opportunities and challenges.
2015
connectionsevents
What makes us human? Or not…
Science & Technology From jumping genes to organ transplants, the non-human features that make us human.
2015
sciencescience-technology
Awards & Honours
EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
embl-announcementslab-matters
Unpacking embryonic pluripotency
Science & Technology Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
sciencescience-technology
Mini DNA sequencer tests true
Science & Technology Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
sciencescience-technology
A snapshot of stem cell expression
Science & Technology Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
sciencescience-technology
A lasting legacy
Science & Technology 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
2015
sciencescience-technology
Marine mysteries
Science & Technology From the role of diatoms to how life evolved - scientists' pressing questions about life in the sea.
2015
sciencescience-technology
Finding links and missing genes
Science & Technology Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
2015
sciencescience-technology
Symposium sails sea of knowledge
Connections Insights from organisers of upcoming EMBO|EMBL Aquatic Microeukaryotes symposium.
2015
connectionsevents
Ages apart
Science & Technology Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.
2015
sciencescience-technology
Awards & Honours
EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
embl-announcementslab-matters
Decoding disease
Science & Technology Behind the scenes of start-up Miroculus, developing a non-invasive test for early-stage disease.
2015
alumniscience-technology
An ocean odyssey
Science & Technology A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.
2015
sciencescience-technology
The French connection
ConnectionsLab Matters EMBL Core Facilities collaborate with French research programme Signalife to revive training visit.
2015
connectionslab-matters
Make it personal
Connections Leading scientists will gather in Heidelberg this November to discuss the potential of personalised health.
2015
connectionsevents
From patients to the lab (and back)
Science & Technology Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children
2015
sciencescience-technology
Know your cells
Science & Technology How T-cells are trained on what not to kill
2015
sciencescience-technology
DNA protection, inch by inch
Science & Technology European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
2015
sciencescience-technology
Decaying RNA molecules tell a story
Decaying RNA molecules tell a story that could add more chapters to the study of ribosomes.
2015
science
Are protein domains indivisible?
New research shows that some proteins domains can function even with big parts missing.
2015
science
When microbes feed each other
Cooperate or compete? Microbes show us that getting along is the better choice for communities.
2015
science
Inside industry: Part I
Lab Matters Career insights from Riccardo Cortese, whose start-up is developing an Ebola vaccine candidate.
2015
alumnilab-matters
Element of surprise
Radiocarbon studies are helping researchers shine light on how neurons stay stable yet adaptable.
2015
science
Curiosity created the ‘Bubome
Lab Matters Exploring the science and magic of Lil Bub – alumna launches project to sequence the ‘Lilbubome’.
2015
alumnilab-matters
Towards an expression atlas for an entire brain
New single-cell genomics techniques bring ‘omics to evolution and development research.
2015
science
Team spirit in the genome
Go Team Genome! New method reveals genetic teamwork in drosophila genome.
2015
science
Why is a dolphin not a cat?
How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Christian Boulin Fellowship
Lab Matters New Christian Boulin Fellowship: 15 awards of up to €1500 for visitors to EMBL’s Core Facilities.
2015
lab-matters
Alumni awards
Lab Matters Announcing winners of the John Kendrew Young Scientist Award, and inaugural Lennart Philipson Award.
2014
alumnilab-matters
Luxembourg collaboration
Lab Matters Third round of calls for joint research projects between EMBL and Luxembourg in 2015
2014
lab-matters
Record parasitic worm dataset
Science & Technology Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
sciencescience-technology
Welcome: Kyung-Min Noh
The important thing is forming good biological questions, says new group leader in Genome Biology.
2014
science
Welcome: Judith Zaugg
Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
2014
science
Next generation training
First series of training courses jointly organised by EMBL and Illumina is a resounding success.
2014
events
11th EMBL Transcription and Chromatin conference
Experts from multiple fields come together to understand how the instructions in genes are read
2014
events
Genotype to phenotype mapping course
EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
Gibbon genome joins Ensembl
Science & Technology Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
sciencescience-technology
How do animals become domesticated?
Science & Technology Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
sciencescience-technology
From students to mentors
Connections PhD students reap rewards and rave reviews as Summer School of Science organisers
2014
connectionsevents
New, improved human genome
Science & Technology Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
sciencescience-technology
New genomics API
Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.
2014
lab-matters
Shedding light on chimeral twins
Science & Technology Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
sciencescience-technology
Back to school
Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’
2014
lab-matters
Five for the future
Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
2014
lab-matters
Taken out of context
Science & Technology Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
sciencescience-technology
Capturing marine biodiversity
Science & Technology Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
sciencescience-technology
Sheep genome provides rich resource for agricultural research
Science & Technology Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
sciencescience-technology
Tsetse fly genome sequenced
Science & Technology Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
sciencescience-technology
A new tree of life allows a closer look at the origin of species
Science & Technology In 1870 the German scientist Ernst Haeckel mapped the evolutionary relationships of plants and animals in the first ‘tree of life’. Since then scientists have continuously redrawn and expanded the tree adding microorganisms and using modern molecular data, yet, many parts of the tree…
2006
sciencescience-technology
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