Gut microbes implicated in bladder cancer
Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.
2024
science-technology
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Father’s gut microbes affect the next generation
Science & Technology Scientists from EMBL Rome and EMBL Heidelberg found that disrupting the gut microbiome of male mice increases the risk of disease in their offspring. Their findings suggest that a father’s pre-conception environment can have lifelong effects on offspring.
2024
science-technology
The secret of molecular promiscuity
EMBLetc Promiscuity is critical for nourishment. How? This question lies at the focus of research by the Löw Group at EMBL Hamburg. Using structural biology methods, they explore how specialised molecules located in the cell membrane allow cells absorb nutrients from their environment.
2023
Spotlight: Colours of the colon
Lab MattersScience & Technology Mucus present in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.
2023
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When microbiomes collide
Science & Technology EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.
2022
sciencescience-technology
The impact of drugs on gut microbes is greater than we thought
Science & Technology Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…
2021
sciencescience-technology
Welcome: Maria Zimmermann-Kogadeeva
Lab MattersPeople & Perspectives Maria Zimmermann-Kogadeeva is one of EMBL’s newest group leaders and a computational biologist whose research group applies computational modelling to better understand the metabolism of gut bacteria and their potential to have far-reaching impacts on other organs.
2021
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Structure of a promiscuous protein will help scientists design better drugs
Science & Technology Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
sciencescience-technology
Tackling the collateral damage from antibiotics
Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…
2021
sciencescience-technology
Transferable skills
Lab MattersPeople & Perspectives In the lab, Diënty Hazenbrink works with microbes that live in our guts. In her free time, she enjoys wildlife photography. A shared set of skills facilitates both activities.
2021
lab-matterspeople-perspectives
Common medications accumulate in gut bacteria
Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
sciencescience-technology
How our gut microbiome changes over time
Science & Technology Researchers investigate how external factors can influence the persistence of microbe species in the human gut
2021
sciencescience-technology
SARS-CoV-2 curtails immune response in the gut
Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
sciencescience-technology
The thousands of viruses living in your gut
Science & Technology Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before
2021
sciencescience-technology
Understanding how SARS-CoV-2 behaves in the gut
Science & Technology Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…
2020
sciencescience-technology
Global microbial signatures for colorectal cancer
Science & Technology Colorectal cancer characterised by consistent changes in gut bacteria across continents, cultures and diets
2019
sciencescience-technology
Many gut microbes may originate in the mouth
Science & Technology Many microbes traverse the oral-gut barrier
2019
sciencescience-technology
Dog microbiome closer to humans’ than expected
People & Perspectives Dog and human gut microbiomes have more similar genes and responses to diet than previously thought
2018
people-perspectivesscience
Commonly used drugs affect our gut bacteria
Science & Technology One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
2018
sciencescience-technology
Molecular cuisine for gut bacteria
Science & Technology EMBL scientists show how to grow a wide range of gut bacteria in the lab
2018
sciencescience-technology
What’s your gut type?
Science & Technology In the future, when you walk into a doctor’s surgery or hospital, you could be asked not just about your allergies and blood group, but also about your gut type. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and collaborators in the international MetaHIT…
2011
sciencescience-technology
Bacterial balance that keeps us healthy
Science & Technology The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…
2010
sciencescience-technology
Life savers in the gut
Science & Technology Researchers from the European Molecular Biology Laboratory (EMBL) have discovered that proteins that regulate the body’s iron household play a vital role in making sure enough nutrients and water are absorbed in the intestine. Mice lacking these proteins suffer from weight loss and…
2008
sciencescience-technology
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