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microscopy

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17 October 2024 SEM image of sponge cells several grey-cylinder like shapes arranged in a circle, with a green spot in the centre.

Seeing is understanding

Imaging lets us observe biology in action – it makes visible the hidden processes of life. From its founding, EMBL has been a centre of breakthroughs and developments in bioimaging, and it continues to play a pioneering role in this field today.

SCIENCE & TECHNOLOGY

2024

science-technology

25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

SCIENCE & TECHNOLOGY

2024

sciencescience-technology

5 October 2023 A composite image of four 3D micrographs showing the cellular organelles of a phytoplankton marked in different colours.

Spotlight: Seeing into the seas

A new method developed by EMBL scientists can help us identify and investigate plankton species in field samples with greater speed, accuracy, and resolution than ever possible before.

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

22 August 2023 Polaroid style shot of Sergiy Avilov, mentioning the years he was at EMBL

After EMBL: Sergiy Avilov

Ukrainian scientist Sergiy Avilov uses the microscopy skills and scientific network he built at EMBL in his current role heading the Imaging Facility at the Max Planck Institute of Immunobiology and Epigenetics.

PEOPLE & PERSPECTIVES

2023

alumnipeople-perspectives

16 May 2023

Managing a bioinformatics core facility

BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.

2023

technology-and-innovation

15 May 2023 A section of electron microscopy volume of a Platynereis larvae. Different colours mark different cell groups.

Visualising biology: new tools of the trade

EMBL researchers are pushing the frontiers of big data analysis in biological imaging, allowing scientists to gain a many-layered and multidimensional view of organisms, tissues, and cells in action.

EMBLetc

2023

3 April 2023 Two male scientists with safety glasses at EMBL Imaging Centre

Dispensing microscopy expertise

Home to some of Europe’s most cutting-edge tools in molecular biology, EMBL has long shared its expertise and access to these tools through an extensive repertoire of courses, conferences, seminars, and other training. And now included in this mix is a job shadowing programme at EMBL Imaging…

LAB MATTERSSCIENCE & TECHNOLOGY

2023

lab-mattersscience-technology

2 November 2022 Fluorescent microscopy image of skeletal muscle with biological data imagery

AI4LIFE: AI models for bioimaging

Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.

2022

announcementsscience

12 October 2022 A group photo taken at the EMBL Heidelberg site, showing members of EMBL and the Ruder Boskovic Institute

EMBL deepens ties with Croatia

Visit of delegation from the Ruđer Bošković Institute to EMBL Heidelberg marks a new chapter in scientific and institutional cooperation

CONNECTIONS

2022

connectionsevents

10 October 2022 Retinal cells can be seen in a cross section. A blue stain (DAPI) marks the cell nuclei, barcoded background cells are visible in green, while a single dopaminergic cell is visible in the centre, marked in orange (Th) and pink (a second barcode).

Light-Seq: from images to sequences in context

Researchers have combined advanced light microscopy with next-generation sequencing to create a method to study cells directly in the context of their native tissues

2022

science

5 August 2022 A rod-like structure with green and magenta segments representing cellular markers.

Making patterns visible

How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

5 May 2022 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

Enabling imaging across scales

EMBL’s first Imaging Centre Symposium will occur onsite at EMBL and include tours of the new Imaging Centre on 31 May, introducing participants to the facility and its staff and featuring talks on the rapid developments in imaging technologies that have led to notable biological and medical…

EMBL ANNOUNCEMENTS

2022

embl-announcementsevents

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

23 September 2021 Pink and blue dominate a blurry image against a black background that is actually a global image of a 30-day-old Octopus vulgaris

The secret life of baby octopuses

Some of the most amazing creatures live in the deep blue sea. The Mesoscopic Imaging Facility (MIF) at EMBL Barcelona was recently involved in studying one unique feature of the octopus: the ephemeral structures on the surface of their skin called Kölliker’s organs.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

23 June 2021 Bright blue oblong shape with white hairs on surface on black background.

Starlet sea anemone

EMBL PhD student Anniek Stokkermans captured this side view of a Nematostella vectensis larva during this transition, using instrumentation in the Advanced Light Microscopy Facility at EMBL Heidelberg.

SCIENCE & TECHNOLOGY

2021

picture-of-the-weekscience-technology

8 June 2021 Purple, blue and yellow dots on a black background.

Dream team

At EMBL, we have many dream teams – groups of individuals who support each other, innovate, and work together. One of those dream teams bridges two core facilities at EMBL Rome.

SCIENCE & TECHNOLOGY

2021

picture-of-the-weekscience-technology

27 October 2020 Microscopic image of a cell, nucleus visible in bright green, cell membrane stained with a purple dye against black background.

Party at the nucleus?

The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.

SCIENCE & TECHNOLOGY

2020

picture-of-the-weekscience-technology

8 October 2020 Alvaro Crevenna, heads EMBL Rome’s Microscopy Facility. Credit: EMBL

Beyond the lens – microscopy at EMBL Rome

Research facilities play a crucial role in the advancement of science by supporting scientists with specialised expertise and state-of-the-art equipment. The Microscopy Facility at EMBL Rome exemplifies this role by making a wide variety of light microscopy technologies available to its researchers…

LAB MATTERSSCIENCE & TECHNOLOGY

2020

lab-mattersscience-technology

7 April 2020

Exciting science!

EMBL is all about exciting science, through which we aim to achieve a fundamental understanding of biological processes.

SCIENCE & TECHNOLOGY

2020

picture-of-the-weekscience-technology

12 March 2018 Robert Prevedel talks about EMBL and microscopy at the Internationale Gesamtschule Heidelberg. PHOTO: EMBL/Hugo Neves

Science in a suitcase

School students build fluorescence microscopes designed by members of the Prevedel group and ELLS

LAB MATTERS

2018

eventslab-matters

17 December 2015 Digital zebrafish embryo provided the first complete developmental blueprint of a vertebrate in 2008. IMAGE: EMBL/Keller et al.

SPIM doctors

From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

26 August 2015 Hands-on sessions were a crucial part of the course. PHOTO: EMBL Photolab/Marietta Schupp

Super impressions

"It's like living a review!" Participants of recent super-resolution microscopy course share their highlights

CONNECTIONS

2015

connectionsevents

25 February 2015 The team used computer simulations to investigate the mitotic spindle's strength. IMAGE: EMBL/F. NÉDÉLEC

Under pressure

How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test

SCIENCE & TECHNOLOGY

2015

sciencescience-technology

18 December 2014

Alumni awards

Announcing winners of the John Kendrew Young Scientist Award, and inaugural Lennart Philipson Award.

LAB MATTERS

2014

alumnilab-matters

12 September 2013

Potential new drug target for cystic fibrosis

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis. Their work, published online today in Cell, also uncovers a…

SCIENCE & TECHNOLOGY

2013

sciencescience-technology

11 July 2013

How to build your gate

It’s a parent’s nightmare: opening a Lego set and being faced with 500 pieces, but no instructions on how to assemble them into the majestic castle shown on the box. Thanks to a new approach by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…

SCIENCE & TECHNOLOGY

2013

sciencescience-technology

3 June 2012 Silenced genes in a cell

Export extravaganza

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells’ export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting…

SCIENCE & TECHNOLOGY

2012

sciencescience-technology

7 August 2011 The new microscope that developed by scientists at EMBL, which can follow single molecules by the millisecond Credit: EMBL/H.Neves.

Live from the scene: biochemistry in action

Researchers can now watch molecules move in living cells, literally millisecond by millisecond, thanks to a new microscope developed by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Published online today in Nature Biotechnology, the new technique provides…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

23 January 2011 Micropilot detected cells at particular stages of cell division

Intelligent microscopy

The sight of a researcher sitting at a microscope for hours, painstakingly searching for the right cells, may soon be a thing of the past, thanks to new software created by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Presented today in Nature Methods, the…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

16 November 2010

One-touch make-up – for our cells

The cells in the different parts of this video are always the same (grey), but, like actors using make-up to highlight different facial features, they have fluorescent labels that mark different cellular components in different colours: blue shows the nucleus, yellow shows tubulin (a component of…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

1 April 2010 Each of these large images of dividing cells is composed of several microscopy images of human cells in which different individual genes were silenced. The smaller images are placed according to genes’ effects: images for genes that affect chromosomes make up the chromosomes (red/pink), while the mitotic spindle (green) is composed of images for genes that affect it. IMAGE: Thomas Walter & Mayumi Isokane / EMBL

Movies for the human genome

Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

24 February 2009 A full body shot of Medaka juveniles, taken by Philipp Keller, from the lab of Ernst Stelzer at the European Molecular Biology Laboratory (EMBL), with a newly developed microscope called Digital Scanned Laser Light Sheet Fluorescence Microscope. Picture credits: Philipp Keller, Stelzer Group, EMBL

Picture Release

‘Useless fish with big eyes’. This is what Medaka, the name of the Japanese killifish in the pictures, means in Japan where it originally comes from. While its eyes are undeniably big, the fish has proven remarkably useful for scientists. It is a simple model organism, amenable to…

SCIENCE & TECHNOLOGY

2009

sciencescience-technology

22 October 2008

Picture Release

What at the first sight could be pictures of planets or other cosmic structures are actually microscope images of balls (cysts) of human kidney cells. They were taken by Emmanuel Reynaud, in the group of Ernst Stelzer at the European Molecular Biology Laboratory (EMBL), with a widefield microscope.…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

4 May 2007

A matter of force

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

4 March 2007

A clearer view on biology

The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

31 March 2005

The transparent organism

A novel high-tech microscope will be brought to the marketplace, giving laboratories everywhere fascinating new insights into living organisms. EMBLEM Technology Transfer GmbH (EMBLEM), the commercial entity of the European Molecular Biology Laboratory (EMBL), announced today that it has signed a…

CONNECTIONS

2005

connections

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