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müller

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9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

sciencescience-technology

8 February 2021 Illustration of a laboratory flask to the left of a microscope against an orange/grey background with a zoomed-in cut-out of the microscope view, which is colourful molecules.

A better look at a human RNA polymerase

Science & Technology New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.

2021

sciencescience-technology

11 July 2019 Structure of the Elongator complex

A tRNA modifier at work

Science & Technology Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.

2019

sciencescience-technology

17 November 2016

New insights into RNA Polymerase I

Science & Technology Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA

2016

sciencescience-technology

30 August 2016 Data by Natalia Wesolowska has been visualised in 3D stereoscopic view, as an anaglyph and a 3D lenticular poster by Stefan Günther & Gustavo de Medeiros at EMBL

See data in a new light

Science & Technology 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research

2016

sciencescience-technology

2 May 2010 These microscopy images show the region of the embryo larva that will develop into the adult fruit fly’s wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) - a situation which is corrected when PR-DUB’s activity is restored (right). Image credits: J.Mueller/EMBL.

Tags on, tags off

During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing specialised tissues and organs from forming in the wrong places. They also play an important role in processes like stem cell differentiation and…

2010

science

28 May 2009

Sugarcoating fruit fly development

Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…

2009

science

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