organoid Archives

3 September 2024 Illustration showing a pair of human hands holding up three petri dishes, with a miniature pancreas, intestines, and lungs respectively.

Illustration showing a pair of human hands holding up three petri dishes, with a miniature pancreas, intestines, and lungs respectively.

Hans Clevers to deliver 2024 Kafatos Lecture on pioneering organoid research

On Friday 4 October 2024 at 18:00 CEST, the Royal Netherlands Academy of Arts and Sciences (KNAW) in Amsterdam will host the 2024 Kafatos Lecture, delivered by renowned scientist Hans Clevers.

EMBL ANNOUNCEMENTS

2024

embl-announcements

15 May 2023 Science illustration representing research on organoids, organs-on-chip, and human health. The abstract composition shows several elements representing research into organoids and microphysiological systems, and their intertwined role in understanding health and disease.

Science illustration representing research on organoids, organs-on-chip, and human health. The abstract composition shows several elements representing research into organoids and microphysiological systems, and their intertwined role in understanding health and disease.

Organs-on-chip: new horizons for disease research

EMBL Barcelona researchers are studying how tissues develop in health and disease using organoids and 3D multicellular systems to mimic human organs and their functions.

EMBLetc

2023

20 October 2022 On th eleft side of the image we see a rounded cell colony in green. Below that image we see a lateral slice of the colony that is flat. On the right side of the image we see a cell colony in green. Below that image we see a lateral slice of the colony that has folded.

On th eleft side of the image we see a rounded cell colony in green. Below that image we see a lateral slice of the colony that is flat. On the right side of the image we see a cell colony in green. Below that image we see a lateral slice of the colony that has folded.

The power of light: folding 3D tissues

EMBL Barcelona researchers have developed a tool that can use light to control the shape of cells .

2022

science

6 May 2022 Two embryonic stem cell aggregates partially fuse

What do stem cell aggregates and whipped cream have in common?

EMBL researchers revise the old problem of sintering droplets to understand the mechanical properties of tissues.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

10 January 2022 Photo of Kristina Haase, roup Leader at EMBL Barcelona

Kristina Haase from EMBL Barcelona receives ERC Starting Grant

Kristina Haase, Group Leader at EMBL Barcelona, will receive €1.5 million over the next five years to develop her project on 3D vascularised in vitro cardiac tissues.

EMBL ANNOUNCEMENTS LAB MATTERS

2022

embl-announcementslab-matters

12 October 2021 Man in white and blue t-shirt in outdoor setting

When ‘good’ cells go ‘bad’

If researchers can identify specifically when good cells go bad, they can potentially understand disease better.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

20 September 2021

The image shows an infographic about how Morgana software works. In the first box, Morgana is fed with images – human brain organoids, zebrafish explants, intestinal organoids, or other – acquired with different microscopy devices – from stereoscopic microscopes to confocal to high content screening microscopes. In the second image it’s portrayed how the platform segments the images with machine learning algorithms. The third box represents quantification in a modular format. That means that it can be adapted to the experiment and organoid type, being able to choose the relevant features for each case.

Organoids and machine learning: image analysis software developed during lockdown

MOrgAna is an open source, user-friendly, modular software that is able to analyse organoids with machine learning.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

27 April 2021 Three irregular shapes, made up of green, blue, red and pink speckles, are set against a black background.

SARS-CoV-2 curtails immune response in the gut

EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

7 December 2020 Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

2 September 2020 Microscopy image of cerebral organoid cross section

An organoid cell atlas to enhance biomedical research

EMBL-EBI is one of the eight European institutes involved in the Humanoid Cell Atlas initiative, a new open-access platform that combines single-cell profiling and organoid technology

EMBL ANNOUNCEMENTS LAB MATTERS

2020

embl-announcementslab-matters

21 July 2020 Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

A tool to improve cancer research

EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

16 June 2020 Tissue culture plates in an incubator.

Understanding how SARS-CoV-2 behaves in the gut

Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

31 December 2019

Tumour takeover

Breast cancer is the second leading cause of cancer-related deaths in women. It is so deadly because tumours often return after successful cancer treatment. This recurrence is caused by individual dormant cancer cells remaining inside the breast. These cells can develop into active cancer cells…

SCIENCE & TECHNOLOGY

2019

picture-of-the-weekscience-technology

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