The Pan-Cancer project
EMBL co-leads most comprehensive study of genetic causes of cancer
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Protecting data in the cloud
Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Characterising RNA alterations in cancer
The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Cancer mutations occur decades before diagnosis
Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Analysis of human genomes in the cloud
Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Studying DNA rearrangement to understand cancer
Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Scientists identify new genetic drivers of cancer
Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Chromothripsis in human cancer
Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Finding genetic cancer risks
Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
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