25 June 2024
Science & Technology
EMBL Grenoble’s Kowalinski Group analysed the structure of an enzyme responsible for modifying tRNA molecules to fine-tune protein production. They discovered that to distinguish almost identical, yet different, tRNA molecules, the enzyme uses help from another enzyme – a type of cooperation…
19 June 2024
Science & Technology
EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…
12 March 2024
People & Perspectives, Perspectives, Science
Team Leader Sameer Velankar on why accessible training is key for AlphaFold and AI tools more generally.
2024
people-perspectivesperspectivesscience
21 December 2023
Science, Science & Technology
The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.
2023
sciencescience-technology
15 November 2023
EMBLetc
Promiscuity is critical for nourishment. How? This question lies at the focus of research by the Löw Group at EMBL Hamburg. Using structural biology methods, they explore how specialised molecules located in the cell membrane allow cells absorb nutrients from their environment.
1 November 2023
Lab Matters, People & Perspectives
In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.
2023
lab-matterspeople-perspectives
26 October 2023
Updates from data resources
In response to user community demands, the AlphaFold Protein Structure database has introduced sequence-based search and cluster members.
2023
updates-from-data-resources
19 September 2023
Science & Technology, Technology and innovation
Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
2023
science-technologytechnology-and-innovation
3 July 2023
Science, Science & Technology
A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…
2023
sciencescience-technology
22 June 2023
Updates from data resources
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
7 June 2023
Announcements, Lab Matters, People & Perspectives
In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
2023
announcementslab-matterspeople-perspectives
17 March 2023
Updates from data resources
EMBL-EBI's metagenomics data resource increases in size and supports groundbreaking AI tools for protein structure prediction.
2023
updates-from-data-resources
7 November 2022
Research highlights, Science
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
23 September 2022
EMBL Announcements, Lab Matters
Cell biologist Anthony Hyman and DeepMind’s Demis Hassabis and John Jumper were announced among 25 Breakthrough Prize recipients
2022
embl-announcementslab-matters
22 August 2022
People & Perspectives, Perspectives, Science
Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
people-perspectivesperspectivesscience
28 July 2022
Science, Science & Technology, Technology and innovation
AlphaFold database offers a look at 3D protein universe.
2022
sciencescience-technologytechnology-and-innovation
6 May 2022
Updates from data resources
New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
7 February 2022
Science, Science & Technology
DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
sciencescience-technology
1 February 2022
Science, Science & Technology
EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.
2022
sciencescience-technology
28 January 2022
Updates from data resources
Latest AlphaFold database update adds 27 new organisms and almost 200,000 new protein structure predictions relevant to neglected tropical diseases and antimicrobial resistance
2022
updates-from-data-resources
17 December 2021
Science, Science & Technology
The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
sciencescience-technology
3 November 2021
Science, Science & Technology
Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
sciencescience-technology
15 October 2021
Science, Science & Technology
The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…
2021
sciencescience-technology
6 October 2021
Science, Science & Technology
Structural biology provides insights into the diverse functions of fibrous protein in humans, amphibians, and bacteria.
2021
sciencescience-technology
27 September 2021
Lab Matters
Hundreds of school children explore the beauty of proteins through art
16 September 2021
Connections, Science
3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
30 August 2021
Lab Matters, Science & Technology
Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
2021
lab-mattersscience-technology
22 July 2021
Science, Science & Technology
Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
sciencescience-technology
22 July 2021
Science, Science & Technology
DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
sciencescience-technology
22 July 2021
Science, Science & Technology
A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
sciencescience-technology
17 May 2021
Science, Science & Technology
Researchers at EMBL Hamburg reveal how peg-like proteins clasp and reshape the cell membrane
2021
sciencescience-technology
20 April 2021
Picture of the week, Science & Technology
What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics simulations to find out.
2021
picture-of-the-weekscience-technology
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