People & Perspectives Maria Costanzo, former predoc at EMBL Barcelona, talks about YAP, her favourite protein in the shape of a heart. This is part of a series of stories about EMBL scientists and quirky, charming proteins that make them smile.
2025
people-perspectives
People & Perspectives Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell’s molecular ‘bubble blower’.
2024
people-perspectives
People & Perspectives Sofia Rucli, postdoc at EMBL Rome, talks about her relationship with the protein OGT, a molecular ‘candy man’ of the cell.
2024
people-perspectives
Science & Technology Scientists from EMBL Hamburg and CSSB have revealed key insights into the cellular process of clathrin-mediated endocytosis.
2024
science-technology
Science & Technology Creators of AI system AlphaFold receive 2024 Nobel Prize for Chemistry.
2024
sciencescience-technology
Traditional sequence search methods are fast and efficient but rely solely on comparing amino acid sequences. This approach can miss crucial insights because proteins with similar functions can have vastly different sequences. Although their sequences have diverged, these proteins often retain 3D…
2024
updates-from-data-resources
Science & Technology EMBL Grenoble’s Kowalinski Group analysed the structure of an enzyme responsible for modifying tRNA molecules to fine-tune protein production. They discovered that to distinguish almost identical, yet different, tRNA molecules, the enzyme uses help from another enzyme – a type of cooperation…
2024
science-technology
Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…
2024
science-technology
People & Perspectives Team Leader Sameer Velankar on why accessible training is key for AlphaFold and AI tools more generally.
2024
people-perspectivesperspectivesscience
Science & Technology The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.
2023
sciencescience-technology
EMBLetc Promiscuity is critical for nourishment. How? This question lies at the focus of research by the Löw Group at EMBL Hamburg. Using structural biology methods, they explore how specialised molecules located in the cell membrane allow cells absorb nutrients from their environment.
2023
Lab MattersPeople & Perspectives In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.
2023
lab-matterspeople-perspectives
In response to user community demands, the AlphaFold Protein Structure database has introduced sequence-based search and cluster members.
2023
updates-from-data-resources
Science & Technology Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
2023
science-technologytechnology-and-innovation
Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…
2023
sciencescience-technology
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
Lab MattersPeople & Perspectives In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
2023
announcementslab-matterspeople-perspectives
EMBL-EBI's metagenomics data resource increases in size and supports groundbreaking AI tools for protein structure prediction.
2023
updates-from-data-resources
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
EMBL AnnouncementsLab Matters Cell biologist Anthony Hyman and DeepMind’s Demis Hassabis and John Jumper were announced among 25 Breakthrough Prize recipients
2022
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People & Perspectives Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
people-perspectivesperspectivesscience
Science & Technology AlphaFold database offers a look at 3D protein universe.
2022
sciencescience-technologytechnology-and-innovation
New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
Science & Technology DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
sciencescience-technology
Science & Technology EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.
2022
sciencescience-technology
Latest AlphaFold database update adds 27 new organisms and almost 200,000 new protein structure predictions relevant to neglected tropical diseases and antimicrobial resistance
2022
updates-from-data-resources
Science & Technology The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
sciencescience-technology
Science & Technology Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
sciencescience-technology
Science & Technology The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…
2021
sciencescience-technology
Science & Technology Structural biology provides insights into the diverse functions of fibrous protein in humans, amphibians, and bacteria.
2021
sciencescience-technology
Lab Matters Hundreds of school children explore the beauty of proteins through art
2021
lab-matters
Connections 3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
2021
connectionsscience
Lab MattersScience & Technology Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
2021
lab-mattersscience-technology
Science & Technology Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
sciencescience-technology
Science & Technology DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
sciencescience-technology
Science & Technology A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
sciencescience-technology
Science & Technology Researchers at EMBL Hamburg reveal how peg-like proteins clasp and reshape the cell membrane
2021
sciencescience-technology
Science & Technology What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics simulations to find out.
2021
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