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proteomics

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25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

SCIENCE & TECHNOLOGY

2024

sciencescience-technology

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

24 February 2022 Expression Atlas database logo - A magnifying glass highlighting a yellow section on a blue background

New Expression Atlas release in collaboration with PRIDE

New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets.  To improve reproducibility,…

2022

updates-from-data-resources

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

16 February 2021 Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Finding coronavirus’s helper proteins

A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

8 June 2020 Microscopic image showing a macrophage that has been infected with Salmonella (green), causing cellular cathepsins (red) to locate to the nucels (blue).

Re-trafficking proteins to fight Salmonella infections

Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

25 June 2014

On target

A new EMBL-EBI biomedical initiative works to determine the best target proteins for new drugs.

CONNECTIONSLAB MATTERS

2014

connectionslab-matters

28 August 2007

Minimum Information Standards ─ all for one and one for all

Three papers published by EMBL scientists and their collaborators will make it much easier to share and compare information from large-scale proteomics data. The papers are published in Nature Biotechnology on 8 and 26 August. As the quantity of available biological information and the use of…

LAB MATTERS

2007

lab-matters

29 August 2005

EBI and Ghent University launch PRIDE

The European Bioinformatics Institute and Flanders Interuniversity Institute for Biotechnology (VIB) – Ghent University have launched the PRoteomics IDEntifications database (PRIDE). PRIDE allows researchers who work in the field of proteomics – the large-scale study of proteins – to…

CONNECTIONSLAB MATTERS

2005

connectionslab-matters

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