Follow the cellular road
Science & Technology An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.
2024
science-technology
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Gut microbes implicated in bladder cancer
Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.
2024
science-technology
‘Invisible’ protein keeps cancer at bay
Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…
2024
science-technology
Unveiling the vulnerabilities of pulmonary neuroendocrine tumours
Science & Technology A new organoid model mimics the behaviour of neuroendocrine tumours (NETs), providing a novel and invaluable tool to study the disease in the lab.
2023
sciencescience-technology
Combi-seq: a leap forward for personalised cancer therapy
Science & Technology Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
2022
sciencescience-technology
A tool to improve cancer research
Science & Technology EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
sciencescience-technology
The Pan-Cancer project
Science & Technology EMBL co-leads most comprehensive study of genetic causes of cancer
2020
sciencescience-technology
Characterising RNA alterations in cancer
Science & Technology The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
2020
sciencescience-technology
Cancer mutations occur decades before diagnosis
Science & Technology Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
2020
sciencescience-technology
Studying DNA rearrangement to understand cancer
Science & Technology Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
2020
sciencescience-technology
Scientists identify new genetic drivers of cancer
Science & Technology Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
2020
sciencescience-technology
Chromothripsis in human cancer
Science & Technology Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
2020
sciencescience-technology
Finding genetic cancer risks
Science & Technology Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.
2020
sciencescience-technology
Miniature testing of drug pairs on tumour biopsies
Science & Technology Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
2018
sciencescience-technology
From fireman to arsonist
Science & Technology Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
2013
sciencescience-technology
One disease, two mechanisms
Science & Technology While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…
2013
sciencescience-technology
A matter of priorities
Science & Technology Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have found. The study, published online today…
2012
sciencescience-technology
A signal that protects the liver from hepatitis and cancer
Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…
2007
science
A new link between stem cells and tumors
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in…
2005
science
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