Science & Technology EMBL Heidelberg researchers compared the effect of drugs on isolated bacteria versus those growing in communities. This is the first study showing that bacteria are more resilient when in community due to cross-protection strategies. This could help researchers design more efficient therapies.
2024
science-technology
People & Perspectives Julia Mahamid and Nassos Typas reflect on the direction of the Molecular Systems Biology Unit they now lead at EMBL Heidelberg.
2024
people-perspectives
Science & Technology In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality.
2023
sciencescience-technology
Lab MattersScience & Technology To identify which drugs disrupt bacterial envelope integrity, the Typas group uses a molecule called chlorophenyl red-β-D-galactopyranoside.
2022
lab-matterspicture-of-the-weekscience-technology
Science & Technology EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.
2022
sciencescience-technology
EMBL AnnouncementsLab Matters Cornelius Gross, Miki Ebisuya and Nassos Typas join EMBO, the prestigious organisation for the life sciences.
2022
embl-announcementslab-matters
Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…
2021
sciencescience-technology
Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
sciencescience-technology
Science & Technology Research in the Typas group uncovers new details of the strategies Salmonella uses to survive in infected cells.
2021
sciencescience-technology
EMBL AnnouncementsLab Matters Nassos Typas has received the German VAAM Research Award.
2021
embl-announcementslab-matters
Science & Technology A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
2021
sciencescience-technology
Science & Technology A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.
2020
sciencescience-technology
EMBL AnnouncementsLab Matters Three changes in senior staff positions have been confirmed at EMBL today. Jessica Vamathevan becomes Head of Strategy, Jan Korbel becomes Head of Data Science for EMBL Heidelberg, and Nassos Typas becomes Senior Scientist.
2020
embl-announcementslab-matters
Science & Technology Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…
2020
sciencescience-technology
Science & Technology Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.
2020
sciencescience-technology
Science & Technology EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells
2020
sciencescience-technology
ConnectionsLab Matters Three international teams involving EMBL Heidelberg have been granted funding from the European Commission for three Twinning projects with institutes in Portugal and the Czech Republic.
2020
connectionslab-matters
Lab Matters Nina Kathe, Winner of the EU Contest for Young Scientists visits EMBL
2018
eventslab-matters
Science & Technology EMBL scientists investigate how bacteria melt to study their reaction to drugs
2018
sciencescience-technology
Science & Technology Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness
2018
sciencescience-technology
Science & Technology One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
2018
sciencescience-technology
Science & Technology EMBL scientists show how to grow a wide range of gut bacteria in the lab
2018
sciencescience-technology
How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
2014
science
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