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unstructural biology

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19 June 2024 In the centre: green angular origami-like shapes stacked on top of each other. Small orange rectangles akin to adhesive tape are placed where the green shapes connect with each other. In the background: a circle in the middle and cancer cells on the left and right.

‘Invisible’ protein keeps cancer at bay

Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…

2024

science-technology

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

2023

sciencescience-technology

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