Science & Technology Scientists have discovered how the antiviral protein TRIM25 finds and binds viral RNA to activate an innate immune response.
2024
science-technology
Science & Technology A new publication from the Cusack group sheds light on how a key avian influenza virus enzyme can mutate to allow the virus to replicate in mammals.
2024
science-technology
Science & Technology The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.
2023
sciencescience-technology
Science & Technology Enabling researchers worldwide to share and analyse pathogen data generated across the world
2023
sciencescience-technologytechnology-and-innovation
Lab MattersPeople & Perspectives Jan Kosinski, Group Leader at EMBL Hamburg and one of the co-chairs of the Infection Biology theme in EMBL’s new programme, chats about how this theme will support his work and help establish new collaborations.
2022
lab-matterspeople-perspectives
Science & Technology Researchers have identified hundreds of new bacterial species and viruses in the human skin microbiome.
2022
sciencescience-technology
Science & Technology The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…
2021
sciencescience-technology
Science & Technology By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells. This work, which holds promise for treating COVID-19, was conducted by EMBL Hamburg and collaborators from the Centre for Structural Systems Biology…
2020
sciencescience-technology
Science & Technology EMBL researchers are studying COVID-19-related molecules by exposing them to high-brilliance X-ray beams. The Svergun group at EMBL Hamburg is using biological small-angle X-ray scattering (SAXS) as part of a global effort by scientists to elucidate the structural organisation of SARS-CoV-2…
2020
sciencescience-technology
Science & Technology The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…
2020
sciencescience-technology
Science & Technology Results from the Tara Oceans expedition reveal the Arctic Ocean as a cradle of viral biodiversity
2019
sciencescience-technology
Lab MattersScience & Technology What does it take to create a vaccine or improve cancer therapies?
2018
lab-mattersscience-technology
Science & Technology EMBL scientists investigate how influenza virus responds to new drug treatment
2018
sciencescience-technology
Science & Technology As a retrovirus matures, the two parts of its shell protein (red and blue or yellow and blue) dramatically rearrange themselves, twisting and moving away from each other. (Credit: EMBL/T.Bharat) Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the…
2012
sciencescience-technology
Science & Technology Influenza is currently a grave concern for governments and health organisations around the world. Now one of the tactics used by influenza virus to take over the machinery of infected cells has been laid bare by structural biologists at the EMBL, the joint Unit of Virus Host-Cell Interaction of…
2008
sciencescience-technology
Science & Technology In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world. There is great concern that this virus might also…
2007
sciencescience-technology
Science & Technology Ebola, measles and rabies are serious threats to public health in developing countries. Despite different symptoms all of the diseases are caused by the same class of viruses that unlike most other living beings carry their genetic information on a single RNA molecule instead of a double strand of…
2006
sciencescience-technology
Science & Technology A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institut de Virologie Moléculaire et Structurale (IVMS), associated with the…
2006
sciencescience-technology
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