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wilmanns

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11 November 2024 Portrait photo of Jan Bláha.

We are EMBL: Jan Bláha on protein crystallisation inside cells

People & Perspectives Jan Bláha, postdoc at EMBL Hamburg, talks about the utility of in cellulo protein crystallisation in structural biology research, his sources of inspiration, and the values of collaboration, curiosity, and resilience.

2024

people-perspectives

19 June 2024 In the centre: green angular origami-like shapes stacked on top of each other. Small orange rectangles akin to adhesive tape are placed where the green shapes connect with each other. In the background: a circle in the middle and cancer cells on the left and right.

‘Invisible’ protein keeps cancer at bay

Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…

2024

science-technology

27 November 2023 Photo of two people brainstorming at the table covered with several papers and images related to the research project, such as the structure of the molecule, a map with the Solar Lake marked, photo of EMBL Hamburg, photo of Garo Antranikian looking into a microscope, pages of the manuscript, data graphs, and more.

Hamburg collaboration paves the way to cleaner technologies for industry

Science & Technology An interdisciplinary collaboration between Hamburg scientists has yielded new insights into the structure and function of a heat-resistant enzyme from an exotic microbe. In this interview, EMBL Hamburg’s Matthias Wilmanns and TUHH’s Garo Antranikian discuss how their collaboration developed and…

2023

sciencescience-technology

1 November 2023 Sihyun Sung is standing next to experimental equipment for time-resolved serial X-ray crystallography. The light in the room is pink.

We are EMBL: Sihyun Sung on time-resolved structural biology

Lab MattersPeople & Perspectives In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.

2023

lab-matterspeople-perspectives

10 May 2023 Illustration showing a cute humanoid-shaped robot that spits pink droplets at a sheet.

Time-resolved crystallography for the masses

Science & Technology EMBL Hamburg scientists have contributed to the development of the Spitrobot, a ground-breaking experimental setup that will simplify creating molecular movies. The Spitrobot automates the sample preparation for time-resolved crystallography, which is used to create 3D snapshots of protein…

2023

sciencescience-technology

1 February 2022 A photograph of the Amazonian lancehead snake Bothrops atrox

Decoding the secrets of snake venom

Science & Technology EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.

2022

sciencescience-technology

6 July 2017

CSSB opens its doors

ConnectionsLab Matters On 29 June, at a ceremony in front of 700 guests, the Centre for Structural Systems Biology (CSSB) in Hamburg, was officially opened. At the event on the Deutsches Elektronen-Synchrotron (DESY) Campus in Hamburg, Helmut Dosch, Chairman of the DESY Board of Directors, presented Head of EMBL Hamburg…

2017

connectionslab-matters

14 June 2016

How cells bag their rubbish

Science & Technology How cells eliminate protein deposits that can lead to neurodegenerative disorders

2016

sciencescience-technology

10 May 2016 A small loop (green) of the atomic structure of DAPK shown to be crucial for dimer formation and binding with its signaling partner Calmodulin. IMAGE: Petra Riedinger/EMBL

Enzyme with a dual-purpose loop

Science & Technology Unexpected results: structure of DAPK enzyme reveals dual-purpose loop

2016

sciencescience-technology

18 January 2016 A peroxisome containing protein crystals is hit by a free-electron laser. IMAGE: EMBL/CFEL, Thomas Seine

The cellular crystal factory

Science & Technology Hamburg collaborators analyse protein crystals inside the cells that made them.

2016

sciencescience-technology

24 November 2015

Awards & Honours

EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

embl-announcementslab-matters

20 February 2015 Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB.

Attack from all sides

Science & Technology Hamburg-led tuberculosis study demonstrates the power of collaboration.

2015

sciencescience-technology

26 January 2015

Light years ahead

Science & Technology As EMBL Hamburg celebrates 40 years, we explore the past, present and future of crystallography.

2015

sciencescience-technology

11 December 2014

Lighting the way

EMBL Hamburg celebrates four decades of vision, pioneering research and beamline services.

2014

events

1 July 2014 Matthias Wilmanns receives his membership certificate

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees

2014

lab-matters

14 February 2011 3D structure of Mycobacterium tuberculosis’ enzyme PriA

Two in one

Science & Technology In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The new findings…

2011

sciencescience-technology

26 January 2010 This image shows the three-dimensional structure of Death-Associated Protein Kinase (green and yellow) when bound to calmodulin (violet and blue). It was obtained by X-ray crystallography. Image credit: Mathias Wilmanns / EMBL

How to shoot the messenger

Science & Technology Cells rely on a range of signalling systems to communicate with each other and to control their own internal workings. Scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now found a way to hack into a vital communications system, raising the possibility of…

2010

sciencescience-technology

11 January 2006

The giant protein titin helps build muscles

Science & Technology Imagine grabbing two snakes by the tail so that they can’t wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and collaborators from King’s College in London have now discovered that something similar happens to a…

2006

sciencescience-technology

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