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yeast

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4 March 2022 Science art expressing the concept of transcriptional neighbourhoods regulating transcript isoform lengths and expression levels.

Understanding genomes, piece by piece

Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

7 December 2020 Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

3 September 2020 Left: Slice of a cell in grey. Right: Two 3D reconstructions of parts of the slice, showing the internal structure.

Nuclear pores in their natural context

Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

4 June 2019

Colourful yeast

Most of us love brewer’s yeast, or at least the food that it’s helped us to produce since ancient times. Without Saccharomyces cerevisiae (its Latin name) we couldn’t enjoy wine, beer or most types of bread. Besides its role in food production, S. cerevisiae is also an important model…

LAB MATTERS

2019

lab-matterspicture-of-the-week

17 June 2011 Condensin loops around several strands of DNA, keeping it coiled up and easier to transport. (Artistic impression) Image credits: EMBL/ P. Riedinger

Keeping it together

As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping. Cells face the same problem when dragging chromosomes apart during cell division. The chromosomes are…

SCIENCE & TECHNOLOGY

2011

sciencescience-technology

18 March 2010

What makes us unique? Not only our genes

Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because…

SCIENCE & TECHNOLOGY

2010

sciencescience-technology

9 July 2008

Zooming in on genetic shuffling

Genetic recombination, the process by which sexually reproducing organisms shuffle their genetic material when producing germ cells, leads to offspring with a new genetic make-up and influences the course of evolution. In the current issue of Nature, researchers at the European Molecular…

SCIENCE & TECHNOLOGY

2008

sciencescience-technology

21 October 2007

Scientists uncover how hormones achieve their effects

New insights into the cellular signal chain through which pheromones stimulate mating in yeast have been gained by scientists at the European Molecular Biology Laboratory [EMBL]. Similar signal chains are found in humans, where they are involved in many important processes such as the…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

6 March 2007

An architectural plan of the cell

Like our body every cell has a skeleton that provides it with a shape, confers rigidity and protects its fragile inner workings. The cytoskeleton is built of long protein filaments that assemble into networks whose overall architecture and fine detail can only be revealed with high resolution…

SCIENCE & TECHNOLOGY

2007

sciencescience-technology

27 September 2006

How nature tinkers with the cellular clock

The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…

SCIENCE & TECHNOLOGY

2006

sciencescience-technology

22 January 2006

The closest look ever at the cell’s machines

Today researchers in Germany announce they have finished the first complete analysis of the “molecular machines” in one of biology’s most important model organisms: S. cerevisiae (baker’s yeast). The study from the biotechnology company Cellzome, in collaboration with the…

SCIENCE & TECHNOLOGY

2006

sciencescience-technology

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